.U.S. Route 18 (US 18) is an east-west U.S. highway in the Midwestern United States. The western terminus is in Orin, Wyoming at an interchange with Interstate 25.
. Its eastern terminus of US 18 is in downtown Milwaukee, Wisconsin. [2] However, US 18 runs concurrent with other U.S. routes from its western terminus to Mule Creek Junction, Wyoming.
. US 18 is one of the original United States highways of 1926. The US 18 designation was originally proposed for a road in Michigan from Grand Haven east to Detroit. This roadway was eventually designated as U.S. Route 16.